Introduction to Computational Neuroscience
Psychology 4/503c - Fall 2007
- General Information.
- Data and Code (secure, need password)
- Other classes in computational neuroscience
- Readings
Week 1: Introduction to Modeling
(Sejnowski, Koch, Churchland, 1988)
Week 2: Introduction to Neuron
(Hines, Carnevale 2001) (Hines, Carnevale 2000)
Week 3: Sodium, Potassium and the Action Potential
(Hodgkin and Huxley, 1952) (Naundorf et al. 2006)
Week 4: The Current Flora
(Khorkova et al. 2007) (Traub et al. 1991)
Week 5: Morphology and Dendritic Integration
(Rall 2003) (Stuart and Spruston 1998)
Week 6: Midterm and Dendritic Processing
Note: Grad students: papers covered are those from week 3-5 included.
Undergraduate students: papers covered are Traub et al 1991 and Stuart and Spruston 1998.
Week 7: Synaptic transmission. The receptor flora
(Wilson Laurent 2005) (Kuhn et. al. 2004)
Week 8: Realistic synaptic transmission- Short term dynamics
(Abbott Regehr 2000) (Purves et. al. 2004: synapse)
Week 9: Small networks and central pattern generators
(Purvis et al, 2007) (Purves et. al. 2004: movement)
Week 11: Large networks and long term synaptic plasticity
(Purves et al. 2004: plasticity) (Song et. al, 2005)
Week 13: Modeling project presentations (see 'Data and Code' page for powerpoint presentations)
Nadia: Influence of dendritic structure on passive and active properties of somatosensory cortical neurons
Angelique: Modeling bee visual neurons
Aaron: Investigations into determinants of local interneuron firing patterns in the insect antennal lobe
Bethany: L-type Ca2+ spiking in prefrontacl pyramidal neurons
Dave: The effect of carbachol on two currents in a model CA1 cell
Zaneta: The effect of carbachol on the optimal input frequency of hippocampal neurons
JD: Acetylcholine and attractor dynamics in neural networks
Week 14: Final
- The final is comprehensive and will cover all the slides presented in class including the final project presentations of week 13.
- Readings are:Graduate students: All papers week 3-11 included.
Undergraduate students: Traub et al 1991, Stuart and Spruston 1998, Purvis et al 2007 and the three Purves et al 2004: synapse, movement and plasticity.- Graduate students: the write up of your project is due the day of the final. 10-15 pages + references. Make sure to divide into: Introduction, Results and Discussion (no 'method' section). Turn in a hard copy, and a zip file containg your code.